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Published July 29, 2024

GnRH antagonists, like elagolix and relugolix, act more rapidly to suppress these hormones without causing the initial surge associated with agonists

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On paediatric potential, these therapies are currently approved in type 2 diabetes from age 12, and the evidence picture in type 1 diabetes is evolving

A small observational study (2023) in the journal *Obesity* suggested additive weight loss in a cohort of 47 patients on both agents, but sample size, lack of randomization, and absence of long-term follow-up prevent firm conclusions

Not everyone needs to take B complex supplements